Lesson · B.2.1

Cell structure and organelles

A clear, organelle-by-organelle guide to eukaryotic cell structure for the HESI A2 Biology subtest, with the function of each part tied to a question you can expect.

ObjectiveB.2.1Read4 minExam weightCell Biology ≈ 24% of Biology

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What you will be able to do

  • Name each major organelle and state its one core function
  • Tell prokaryotic and eukaryotic cells apart by structure, not by size
  • Match a cell's organelle mix to the job that cell does in the body

What the lesson concludes

  • The nucleus stores and protects the cell's DNA; everything else in the cell carries out what the DNA instructs.
  • Rough ER and free ribosomes build proteins; smooth ER builds lipids and clears drugs and waste.
  • Mitochondria make ATP through cellular respiration, and cells with heavy energy demands pack in more of them.
  • Lysosomes digest material inside the cell using enzymes that only work well in an acidic environment.
  • Prokaryotic cells (bacteria) have no nucleus and no membrane-bound organelles; eukaryotic cells have both.