Lesson · B.2.2

The cell membrane and transport

How the phospholipid bilayer controls what enters and leaves a cell, and how to tell passive transport apart from active transport on the HESI A2 Biology subtest.

ObjectiveB.2.2Read5 minExam weightCell Biology ≈ 24% of Biology

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What you will be able to do

  • Describe the fluid mosaic structure of the plasma membrane and explain why it is selectively permeable.
  • Sort a transport process into passive or active based on whether it needs energy.
  • Name each passive transport route, diffusion, facilitated diffusion, and osmosis, and say what each one moves.

What the lesson concludes

  • The membrane is a phospholipid bilayer with hydrophilic heads facing out and hydrophobic tails facing in.
  • Passive transport follows the concentration gradient and costs no cellular energy.
  • Active transport moves a substance against its gradient and always costs ATP.
  • Osmosis is simply the diffusion of water across a selectively permeable membrane.
  • Endocytosis and exocytosis move whole particles or fluid across the membrane in vesicles, not through channels.